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The Effect of Ethanol Intoxication on the Spectral Characteristics
for Blood Components of White Rats
1Korobova O., 1Dudok T., 1Trach
I., 2Moroz O., 3Vlokh I., 1Vlokh R.
1Institute of Physical Optics, 23 Dragomanov
Str., 79005, Lviv, Ukraine
2Scientific Research Laboratory, National
Medical University, 69 Pekarska Str., 79010, Lviv, Ukraine
3Department of Psychiatry, Psychology
and Sexology, National Medical University, 95 Kulparkivska Str., 79010,
Lviv, Ukraine
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The present paper is devoted to studying, with the aid of different
organic dyes, the transmittance spectra of hemoglobin and immunoglobulin
G extracted from the blood of laboratory rats, which have been chronically
intoxicated with ethanol. The differences in the spectra are detected,
when compare with those for the control group. It is shown that the presence
of ethanol in blood probably leads to uncoiling partially the hemoglobin
molecules. The essential difference is also found in the transmission spectra
of immunoglobulin-dye solution prepared from the blood of the control-group
animals and those of the animals of the first generation. The IgG of blood
plasma of the first-generation rats probably includes a larger quantity
of free remains, which could couple with the intoxicated agents. The small
difference between the IgG-dye solution spectra for the animals given to
drink ethanol during 6 months and the control-group animals is quite possibly
referred to decreasing the IgG concentration after a durable ethanol intake.
Key words: transmission spectra, alcohol intoxication, laboratory
rats, hemoglobin, immunoglobulin G.
PACS: 42.66.-p, 33.55.-b
doi 10.3116/16091833/4/4/161/2003 |
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