Ukrainian Journal of Physical Optics 


Number  4, Volume 6,  2005

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Optical Spectra of Hemoglobin Taken from Alcohol Dependent Humans 
1,2Dudok K., 2Dudok T., 3,2Vlokh I., 1Fedorovich A.M., 2Vlokh R.

1Biochemical Department, Lviv National University, 4 Hrushevsky St., 79005 Lviv, Ukraine
2Institute of Physical Optics, 23 Dragomanov St., 79005 Lviv, Ukraine
3Department of Psychiatry, Psychology and Sexology, State Medical University, 95 Kulparkivska St., 79010 Lviv, Ukraine

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Optical spectra of CNMetHb and CNMetHb-Coomassi G-250, taken from the blood of humans with alcohol dependence, are studied in the spectral range of 450–750nm. The shifts in the spectral absorption maxima of CNMetHb-Coomassi G-250 complexes are observed for the diseased persons with alcohol dependence. The obtained results show that the hemoglobin structure of alcohol dependent humans is changed.

Keywords: absorption spectra, hemoglobin, alcoholism
PACS: 42.66.-p, 33.55.-b

doi 10.3116/16091833/6/4/142/2005
 

1. Zima T, Albano E, Ingelman-Sundberg M, Arteel GE, Thiele GM, Klassen LW, and Sun AY, 2005. Alcohol. Clin. Exp. Res. 29: 1060.
        doi:10.1097/01.ALC.0000168168.43419.54 http://dx.doi.org/10.1097/01.ALC.0000168168.43419.54
2. Hazelett SE, Liebelt RA, Brown WJ, Androulakakis V, Jarjoura D, and Truitt EB, 1998. Alcohol. Clin.Exp. Res. 22: 1813.
3. Braun KP, Cody RBJr, Jones DR, and Peterson CM, 1995. J. Biol. Chem. 270: 11263.
        doi:10.1074/jbc.270.19.11263 http://dx.doi.org/10.1074/jbc.270.19.11263
4. Braun KP, Pavlovich JG, Jones DR and Peterson CM, 1997. Alcohol. Clin. Exp. Res. 21: 40.
5. Hoberman HD, and Chiodo SM, 1982. Alcohol. Clin. Exp. Res. 6: 260.
6. Perutz MF, 1979. Ann. Rev. Biochem. 48: 327.
        doi:10.1146/annurev.bi.48.070179.001551 http://dx.doi.org/10.1146/annurev.bi.48.070179.001551
7. Cordone L, Cupane A, Leone M, and Vitrano E, 1986. Biophys. Chem. 24: 259.
        doi:10.1016/0301-4622(86)85031-1 http://dx.doi.org/10.1016/0301-4622(86)85031-1
8. Dudok KP, Moroz OM, Dudok T, Vlokh I, and Vlokh R, 2004. Ukr. J. Phys. Opt. 5: 32.
        doi:10.3116/16091833/5/1/32/2004 http://dx.doi.org/10.3116/16091833/5/1/32/2004
9. Dudok KP, Vlokh R, Vlokh I, Dudok TH, Fedorovich AM, Moroz OM, and Grinchishin NM, 2004. Ukr. J. Phys. Opt. 5: 104.
        doi:10.3116/16091833/5/3/104/2004 http://dx.doi.org/10.3116/16091833/5/3/104/2004
10. Drabkin DL, 1946. J. Biol. Chem. 164: 703.
11. Kushakovskiy IS, 1968. Clinical forms of hemoglobin damage. Leningrad: 230.
12. Korobova O, Dudok T, Trach I, Moroz O, Vlokh I, and Vlokh R, 2003. Ukr. J. Phys. Opt. 4: 161.
        doi:10.3116/16091833/4/4/161/2003 http://dx.doi.org/10.3116/16091833/4/4/161/2003

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